module, first cell traces are split into responsive and non-responsive depending on the RS from the queried compound and then, if Just about every group is made up of not less than 3 samples, the transcriptional profiles of responsive and non-responsive mobile traces can be analyzed utilizing possibly SAM (Significance Evaluation of Microarray; (19)) or even a t
To discover putative mechanisms of drug resistance in cancers with BRAF mutations, we very first recognized drugs active in most cancers cell strains with BRAF missense mutations using the from gene to drug
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et al. MDP, a databases linking drug response data to genomic info, identifies dasatinib and statins as being a combinatorial technique to inhibit YAP/TAZ in cancer cells
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